Easy Mexican Lasagna Recipe: Cheesy Layered Mexican Casserole

This Mexican Lasagna Casserole layers a savory meat sauce made with salsa, soft tortillas, and plenty of melted cheese. It’s an easy, crowd-pleasing weeknight dinner that comes together with minimal fuss.

A Scoop of Lasagna Hovering Over the Rest of the Casserole in a Glass Pan

An Easy Mexican Dinner Idea

When weeknights are busy, I love dinners that require minimal hands-on time—just spoon into a baking dish and bake. This Mexican “lasagna” is exactly that: the bright, familiar flavors of tacos and enchiladas combined into a simple layered casserole.

It’s flexible, feeds a crowd, and smells amazing while baking. You can adapt it to what you have on hand or to fit dietary needs, making it a reliable go-to for family meals.

A Mexican Lasagna Casserole in a Clear Baking Dish

What is Mexican Lasagna?

Traditional lasagna uses pasta, tomato sauce and cheese in layers. Mexican lasagna swaps those elements for flavors from Mexican cuisine: ground meat simmered with salsa becomes the sauce, soft corn tortillas replace pasta sheets, and cheddar (or a Mexican cheese blend) melts between the layers.

It’s similar to stacked enchiladas but avoids individually rolling tortillas. I often add black beans, corn, onions and bell pepper for color and nutrition, turning it into a complete one-dish meal.

A Pan of Mexican Lasagna Topped with Chopped Parsley and Olives

What You’ll Need

Use this ingredient list as a base and customize as you like.

  • Ground beef: 2 pounds (ground chuck or sirloin work well)
  • Olive oil: 2 tablespoons for sautéing
  • Chili powder: 1 tablespoon for taco-style flavor
  • Ground coriander: 1 tablespoon
  • Salt and pepper: to taste
  • Cumin: 1/2 tablespoon
  • Black beans: 1 (15-ounce) can, drained and rinsed
  • Onion: 1 small, diced (red or yellow)
  • Red bell pepper: 1, diced (or any color)
  • Corn: 1 cup, fresh or frozen
  • Garlic: 2 cloves, minced
  • Salsa: 1 (15-ounce) jar
  • Cheese: 4 cups shredded cheddar (or a Mexican blend)
  • Tortillas: twelve 8-inch corn tortillas (or flour tortillas if preferred)
Black Beans, Corn, Diced Onions, Chili Powder and the Remaining Casserole Ingredients on a Countertop

How To Make Mexican Lasagna

This recipe is great for getting kids involved: older helpers can chop and cook with supervision, while younger ones can layer tortillas and sprinkle cheese. Keep safety in mind around hot pans and knives.

  • Prep oven & pan: Preheat oven to 425°F and spray a 9×13-inch baking dish with cooking spray.
  • Make the sauce: Heat olive oil in a large skillet over medium-high heat. Add ground beef, chili powder, coriander, salt, pepper and cumin. Cook about 5 minutes, breaking up the meat.
  • Stir in black beans, diced onion, bell pepper, corn and garlic. Cook another 5 minutes, then lower the heat and stir in the salsa. Simmer about 7 minutes so flavors meld.
  • Corn, Ground Beef and Black Beans in a Skillet with Mexican Spices
  • A Pan Filled with Mexican Lasagna Filling Beside Three Soft Tortillas
  • Assemble the casserole: Line the bottom of the prepared dish with tortillas, overlapping slightly. Spoon one-third of the beef mixture over the tortillas and spread evenly. Sprinkle one-third of the cheese. Repeat two more times, finishing with cheese on top.
  • Bake: Bake 20–25 minutes, until hot and bubbly. Remove from oven and let rest 10 minutes before slicing and serving.
A Glass Casserole Dish Filled with Mexican Lasagna on a Countertop

Variation Ideas

Customize this recipe to suit your tastes or pantry:

  • Protein: Swap ground beef for shredded chicken, pulled pork, crumbled tofu, or omit meat for a vegetable-forward casserole.
  • Sauce options: Try salsa verde, enchilada sauce, or add chipotle in adobo or a touch of cream cheese or mole for different flavor profiles.
  • Cheese: Mix in Monterey Jack, pepper jack, or a Mexican cheese blend. Dollops of queso fresco or queso blanco add richness.
  • Tortilla alternatives: Use flour tortillas or thin slices of sautéed zucchini for a lower-carb option.
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Tips for Success

Simple techniques will improve the final dish:

  • Thicken the sauce: If the sauce seems thin, whisk 1 tablespoon flour or cornstarch with 1 tablespoon water into a slurry, then stir it into the sauce and simmer a few minutes until thickened.
  • Prevent soggy tortillas: Lightly frying tortillas for a few seconds per side can add flavor and help them hold texture, though it’s optional.
  • Toppings: Serve with sour cream, pico de gallo, cilantro, olives, or sliced jalapeños so everyone can customize their plate.
A Taco Casserole in a Glass Pan on Top of a White and Tan Dish Towel

How To Store & Reheat Leftovers

  • Store leftovers covered in the refrigerator for up to 3 days.
  • Reheat in a 350°F oven until heated through, or microwave individual portions.

Can I Freeze Mexican Lasagna?

  • Yes. Assemble the whole lasagna, wrap tightly, and freeze before baking for up to three months. Thaw overnight in the fridge before baking.
  • Or freeze the cooked filling in a sealed bag for an easy future assembly—thaw overnight and layer into tortillas the day you plan to bake.

Mexican Lasagna

This casserole features a meat sauce made with salsa, layers of soft tortillas and plenty of melted cheese—an easy weeknight favorite.
Prep Time: 25 minutes
Cook Time: 30 minutes
Total Time: 55 minutes
Servings: 10

Ingredients

  • 2 pounds ground beef
  • 2 tablespoons olive oil
  • 1 tablespoon chili powder
  • 1 tablespoon ground coriander
  • Salt and pepper, to taste
  • 1/2 tablespoon cumin
  • 1 (15-ounce) can black beans, drained and rinsed
  • 1 small red onion, diced
  • 1 red bell pepper, diced
  • 1 cup corn kernels, fresh or frozen
  • 2 cloves garlic, minced
  • 1 (15-ounce) jar salsa
  • 4 cups shredded cheddar cheese
  • 12 8-inch corn tortillas

Instructions

  1. Preheat oven to 425°F and grease a 9×13-inch baking dish.
  2. Heat oil in a skillet over medium-high heat.
  3. Add ground beef with chili powder, coriander, salt, pepper and cumin. Cook 5 minutes, breaking up the meat.
  4. Add onion, black beans, bell pepper, corn and garlic; cook 5 more minutes.
  5. Lower heat, stir in salsa, and simmer 7 minutes to combine flavors.
  6. Line the baking dish with overlapping tortillas. Spoon one-third of the beef mixture over the tortillas and spread into an even layer. Sprinkle one-third of the cheese. Repeat twice more, finishing with cheese.
  7. Bake 20–25 minutes until hot and bubbly. Let stand 10 minutes before serving.

Equipment

  • Oven

Nutrition

Calories: 494 kcal | Carbohydrates: 33 g | Protein: 38 g | Fat: 24 g (estimates). Nutritional values are approximate and may vary based on ingredients and portions.

More Casseroles to Try

If you enjoy this casserole, try other easy bakes for weeknights.

  • Gnocchi and Bacon Casserole
  • Eggs Benedict Casserole
  • Cheesy Zucchini and Squash Casserole